Definitive biological links between African ancestry and disease processes that affect an aggressive cancer type called triple-negative breast cancer (TNBC) have been identified by Weill Cornell Medicine investigators. Their analysis of TNBC tumors from a diverse patient population yielded a large set of genes whose expression differed in patients with African ancestry compared with patients …
Treatment outcomes were similar between Black and non-Black patients with Triple-Negative Breast Cancer (TNBC) who received the drug neoadjuvant durvalumab (Imfinzi) plus chemotherapy, according to new clinical trial results. Previous research demonstrated that the drug in combination with chemotherapy prior to surgery benefited patients with non-metastatic TNBC, but the study population did not reflect the …
Hispanic women had the lowest five-year survival from Triple Negative Breast Cancer (TNBC) at 10.7%, compared to Black women at 11.8% and White women at 13.1%, in a study of 26,963 women diagnosed with TNBC between 2010 and 2016. Higher proportions of Hispanic (16.8%) and Black women (9.0%) were diagnosed with TNBC before the age …
In a study of 121 women with triple-negative breast cancer, Black women were younger (by an average of 4 years) and more likely to be obese and have high blood pressure compared with White women. This higher prevalence of cardiovascular risk factors could put them at higher risk for cardiotoxicity from chemotherapy, according to researchers …
Black women diagnosed with Triple Negative Breast Cancer (TNBC) were more frequently unable to receive or declined genetic testing for BRCA mutations compared with White women, according to a survey of 577 patients aged 60 or younger in four hospital systems from 2015 through 2020. The National Comprehensive Cancer Network now recommends this testing for …
Black women were 22 percent more likely than White women to suffer “rapid relapse” of Triple Negative Breast Cancer (TNBC) in a study of more than 17,000 women diagnosed with TNBC between 2010 and 2014 led by researcher Samilia Obeng-Gyasi, MD (above). About a tenth of women with Triple Negative Breast Cancer (TNBC) have what’s …
Black women more likely than White women to suffer rapid relapse of TNBC Read More »
In a study of 23,123 women diagnosed with triple negative breast cancer between 2010 and 2015, Black women were 16 percent more likely than White women to die from the cancer. This disparity in mortality was partially explained by the finding that Black women were 31 percent less likely to receive surgery and 11 percent …
African American women with nonmetastatic triple-negative breast cancer (TNBC) had a significantly higher risk of breast-cancer mortality compared with White women, according to a study of 23,213 U.S. patients diagnosed with the cancer from 2010 to 2015. Compared with White women, African American women diagnosed with TNBC were less likely to be treated with surgery …
Black women more likely to die from Triple-Negative Breast Cancer Read More »
Triple Negative Breast Cancer is more common among African American and western sub-Saharan African breast cancer patients compared with White/Caucasian Americans. In a number of studies, striking similarities in disease epidemiology, risk factors, tumor biology, and genetics were observed between African and African American breast cancer patients, suggesting that West African ancestry is associated with …
Racial Disparities in Triple Negative Breast Cancer Read More »
Not only is there a higher prevalence of triple-negative breast cancer in African American women, they tend to be diagnosed at a more advanced stage, says Coral Omene, MD, PhD (above), medical oncologist at Rutgers Cancer Institute of New Jersey. Compared with other subtypes of breast cancer, they have different risk factors for this disease. …
Information provided on this website is neither intended nor implied to be a substitute for professional medical advice and is not intended to replace the services of a physician.
You should not use information on this web site or the information on links from this site to diagnose or treat a health problem or disease without consulting with a qualified healthcare provider.
